Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Failures of feedback: rush hour along the highway to obesity.

Clinical laboratory science : journal of the American Society for Medical Technology - 1 Jan 2010

Gade Wayne, Gade Jean, Collins Melissa, Schmit Jessica, Schupp Nicole

Abstract excerpt

From hot dogs to Hashimoto's and inheritance to inactivity, many "entrance ramps" converge onto the "Highway to Obesity", each contributing caloric intake that exceeds expenditure. Initially, the hypothalamus regulates appetite and energy based on leptin feedback, until feedback failure increases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Feedback, Physiological
Share to Genetic Predisposition to Disease
Share to Leptin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Obesity

Source

Identifiers

PMID: 20218094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20218094-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Failures of feedback: rush hour along the highway to obesity.PMID 20218094Read ↗

[Part II] Metabolic Overload: How Modern Diets Break the BodySemantic proximity Read ↗

Highway to the danger zone? A cautionary account that GLP-1 receptor agonists may be too effective for unmonitored weight lossSemantic proximity Read ↗

The evolution of body fatness: trading off disease and predation riskSemantic proximity Read ↗

Central regulation of energy homeostasis intelligent design: how to build the perfect survivor.Semantic proximity Read ↗

Obesity: an evolutionary contextSemantic proximity Read ↗

Whole body MondoA deletion protects against diet-induced obesity through uncontrolled multi-organ substrate utilization and futile cyclingSemantic proximity Read ↗

Getting away from glucose: fanning the flames of obesity-induced inflammationSemantic proximity Read ↗

The big problem: battling companion animal obesity.Semantic proximity Read ↗

Biological control of appetite: A daunting complexity.Semantic proximity Read ↗

Carbohydrate-insulin model: does the conventional view of obesity reverse cause and effect?Semantic proximity Read ↗

Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation: review and update.Semantic proximity Read ↗

Adiposity signaling and biological defense against weight gain: absence of protection or central hormone resistance?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.