Article
[Pathogenic patterns of genetic predisposition to endocrine tumors].
Nephrologie & therapeutique - 1 Jan 2006
Calender Alain
Abstract excerpt
Multiple endocrine neoplasia (MEN) are major predisposition syndromes to endocrine tumours and are characterised by an autosomal dominant disorder and full penetrance. MEN-1 is a major form of hyperparathyroidism associated with a high prevalence of endocrine tumours of the pancreas, pituitary gland, adrenal cortex and the lymphoid and bronchial endocrine tissues. MEN-2 is the familial syndrome of medullary...
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