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Secretion of RTX Leukotoxin by <i>Actinobacillus actinomycetemcomitans</i>

1 Nov 2000

Abstract excerpt

Actinobacillus actinomycetemcomitans, the etiologic agent for localized juvenile periodontitis and certain other human infections, such as endocarditis, expresses a leukotoxin that acts on polymorphonuclear leukocytes and macrophages. Leukotoxin is a member of the highly conserved repeat toxin (RTX) family of bacterial toxins expressed by a variety of pathogenic bacteria. While the RTX toxins of other bacterial...

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PMID: 11035711
DOI: 10.1128/iai.68.11.6094-6100.2000

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