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Article

Longitudinal genotyping of Candida dubliniensis isolates reveals strain maintenance, microevolution, and the emergence of itraconazole resistance.

Journal of clinical microbiology - 1 May 2010

Fleischhacker M, Pasligh J, Moran G, Ruhnke M

Abstract excerpt

We investigated the population structure of 208 Candida dubliniensis isolates obtained from 29 patients (25 human immunodeficiency virus [HIV] positive and 4 HIV negative) as part of a longitudinal study. The isolates were identified as C. dubliniensis by arbitrarily primed PCR (AP-PCR) and then genotyped using the Cd25 probe specific for C. dubliniensis. The majority of the isolates (55 of 58) were unique to...

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Identifiers

PMID: 20200288
DOI: 10.1128/JCM.01522-09
PMCID: PMC2863881

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