Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk of Tumorigenesis in First-in-Human Trials of Embryonic Stem Cell Neural Derivatives: Ethics in the Face of Long-Term Uncertainty

14 Jul 2009

Abstract excerpt

While the successful differentiation of human embryonic stem cells into high purity populations of specialized cells is viewed as a major step towards the safety of prospective human transplantation trials, concerns about the possible risks of tumor formation remain. The potential tumorigenicity of transplants derived from embryonic stem cells raises distinctive ethical challenges regarding trial design,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20183160
DOI: 10.1080/08989620903065145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk of Tumorigenesis in First-in-Human Trials of Embryonic Stem Cell Neural Derivatives: Ethics in the Face of Long-Term UncertaintyPMID 20183160Read ↗

Ensuring Safety in Stem Cell Therapies: A Review of Tumorigenic Risks and Mitigation StrategiesSemantic proximity Read ↗

Tumorigenicity risk of iPSCs <i>in vivo</i>: nip it in the budSemantic proximity Read ↗

Concise Review: Scientific and Ethical Roadblocks to Human Embryonic Stem Cell TherapySemantic proximity Read ↗

Tumor-homing cytotoxic human induced neural stem cells for cancer therapySemantic proximity Read ↗

Evaluating the First-in-Human Clinical Trial of a Human Embryonic Stem Cell-Based TherapySemantic proximity Read ↗

Adapting Preclinical Benchmarks for First-in-Human Trials of Human Embryonic Stem Cell-Based Therapies.Semantic proximity Read ↗

Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseasesSemantic proximity Read ↗

First-in-human Phase 1 CRISPR Gene Editing Cancer Trials: Are We Ready?Semantic proximity Read ↗

Safety issues in cell-based intervention trials.Semantic proximity Read ↗

Target Populations for First-In-Human Embryonic Stem Cell Research in Spinal Cord InjurySemantic proximity Read ↗

Filling the gaps in the risks vs. benefits of mammalian adult-cell cloning: taking Bernard Rollin's philosophy its next step.Semantic proximity Read ↗

Development of an optimized, non-stem cell line for intranasal delivery of therapeutic cargo to the central nervous systemSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.