Article
A molecular strategy for routine preimplantation genetic diagnosis in both reciprocal and Robertsonian translocation carriers.
Molecular human reproduction - 1 May 2010
Traversa M V, Carey L, Leigh D
Abstract excerpt
Preimplantation genetic diagnosis (PGD) for structural chromosome abnormalities traditionally uses fluorescence in situ hybridization (FISH) techniques. Although relatively straight forward, FISH is technically demanding with several process problems which include cell loss, cell overlap, variabl...
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