Article
MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling.
American journal of physiology. Gastrointestinal and liver physiology - 1 Apr 2010
Marquez Rebecca T, Wendlandt Erik, Galle Courtney Searcey, Keck Kathy, McCaffrey Anton P
Abstract excerpt
During liver regeneration, normally quiescent liver cells reenter the cell cycle, nonparenchymal and parenchymal cells divide, and proper liver architecture is restored. The gene expression programs regulating these transitions are not completely understood. MicroRNAs are a newly discovered class...
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