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Article

Role of biased hypermutation in evolution of subacute sclerosing panencephalitis virus from progenitor acute measles virus.

Journal of virology - 1 May 1991

Wong T C, Ayata M, Ueda S, Hirano A

Abstract excerpt

We identified an acute measles virus (Nagahata strain) closely related to a defective virus (Biken strain) isolated from a patient with subacute sclerosing panencephalitis (SSPE). The proteins of Nagahata strain measles virus are antigenically and electrophoretically similar to the proteins of Edmonston strain measles virus. However, the nucleotide sequence of the Nagahata matrix (M) gene is significantly...

Topics

Animals
Base Sequence
Biological Evolution
Child, Preschool
Cricetinae
Genes, Viral
Humans
Measles
Measles virus
Molecular Sequence Data
Mutation
RNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

SSPE Virus

Sequence Homology, Nucleic Acid

Viral Matrix Proteins

Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 2016756
DOI: 10.1128/JVI.65.5.2191-2199.1991
PMCID: PMC240566

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2016756-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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