Article
Haptoglobin phenotype correlates with the extent of cerebral deep white matter lesions in hypertensive patients.
Current neurovascular research - 1 Feb 2010
Staals Julie, Henskens Léon H G, Delanghe Joris R, van Oostenbrugge Robert J, Kessels Alfons G, Kroon Abraham A, de Leeuw Peter W, Lodder Jan
Abstract excerpt
Cerebral white matter lesions (WMLs), due to small vessel disease, can be regarded as an early "silent" sign of hypertensive cerebral end-organ damage. As haptoglobin (Hp) phenotype has earlier been associated with symptomatic vascular disease, we now examined the relationship between Hp phenotype and asymptomatic cerebral small vessel disease, manifested by deep and periventricular WMLs, in hypertensive...
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