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Article

Serum markers of apoptosis decrease with age and cancer stage

14 Jul 2009

Abstract excerpt

The physical manifestations of aging reflect a loss of homeostasis that effects molecular, cellular and organ system functional capacity. As a sentinel homeostatic pathway, changes in apoptosis can have pathophysiological consequences in both aging and disease. To assess baseline global apoptosis balance, sera from 204 clinically normal subjects had levels of sFas (inhibitor of apoptosis), sFasL (stimulator of...

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PMID: 20157546
DOI: 10.18632/aging.100069

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