Humoral immunodeficiency in T-cell chronic lymphocytic leukemia. An immunologic assessment.

doi:10.1002/1097-0142(19910515)67:10<2518::aid-cncr2820671022>3.0.co;2-l

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Article

Humoral immunodeficiency in T-cell chronic lymphocytic leukemia. An immunologic assessment.

Cancer - 15 May 1991

Raziuddin S, Sheikha A, Teklu B

Abstract excerpt

The humoral antibody immunodeficiency in two patients with T-cell chronic lymphocytic leukemia (T-CLL) appeared to be the result of immunoregulatory abnormalities in the leukemic T-cell populations. Both patients had CD4+ CD45R+ "virgin" or suppressor-inducer T-CLL, but Patient 1 had hypogammaglo...

Topics

Aged
Aged, 80 and over
Antibody Formation
Antigens, Surface
B-Lymphocytes
Concanavalin A
Humans
Immunoglobulin G
Immunoglobulin M
Interleukin-2
Leukemia, Prolymphocytic, T-Cell
Male
Phenotype
Phytohemagglutinins
T-Lymphocytes

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