Article
Humoral immunodeficiency in T-cell chronic lymphocytic leukemia. An immunologic assessment.
Cancer - 15 May 1991
Raziuddin S, Sheikha A, Teklu B
Abstract excerpt
The humoral antibody immunodeficiency in two patients with T-cell chronic lymphocytic leukemia (T-CLL) appeared to be the result of immunoregulatory abnormalities in the leukemic T-cell populations. Both patients had CD4+ CD45R+ "virgin" or suppressor-inducer T-CLL, but Patient 1 had hypogammaglobulinemia and Patient 2, immunoglobulin (Ig) M hypergammaglobulinemia. Although, CD25+ interleukin-2 (IL-2) receptors...
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