Article
Influence of immunosuppressive therapy on the natural history of genotype 3 hepatitis-E virus infection after organ transplantation.
Transplantation - 15 Feb 2010
Kamar Nassim, Abravanel Florence, Selves Janick, Garrouste Cyril, Esposito Laure, Lavayssière Laurence, Cointault Olivier, Ribes David, Cardeau Isabelle, Nogier Marie Béatrice, Mansuy Jean Michel, Muscari Fabrice, Peron Jean Marie, Izopet Jacques, Rostaing Lionel
Abstract excerpt
BACKGROUND: Hepatitis-E virus (HEV) infection can be responsible for chronic hepatitis in solid-organ transplant patients. METHODS: We identified 33 cases of autochthonous acute HEV infection in solid-organ transplant patients. RESULTS: Among 27 HEV-positive patients, who had a follow-up of more than 6 months, 16 (59.25%) evolved to chronic HEV infection, defined by persisting elevated liver-enzyme levels and...
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