Article
Resistance and virological response analyses in a three initial treatment strategy trial: a substudy of the INITIO trial.
HIV clinical trials - 1 Jan 2000
Descamps Diane, Chazallon Corine, Loveday Clive, Bacheler Lee, Goodall Ruth, Yéni Patrick, Cooper David A, Babiker Abdel, Aboulker Jean-Pierre, Brun-Vézinet Francoise
Abstract excerpt
PURPOSE: To study the impact of baseline resistance mutations and HIV-1 subtypes on virological response to first-line antiretroviral therapy and to analyse the concordance of the results of two antiretroviral resistance interpretation tools in the INITIO trial. METHOD: Genotype and virco TYPE resistance analyses were studied at baseline, Year 2, Year 3, and at first therapeutic failure on plasma specimens stored...
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