Mitotic and meiotic behaviour of a naturally transmitted ring Y chromosome: reproductive risk evaluation

doi:10.1093/humrep/deh598

Article

Mitotic and meiotic behaviour of a naturally transmitted ring Y chromosome: reproductive risk evaluation

5 Nov 2004

Abstract excerpt

BACKGROUND: The mitotic and meiotic behaviour of a transmitted ring Y [r(Y)] chromosome from a father to his Klinefelter syndrome (KS) son, and the mechanism of ring formation are analysed herein. To our knowledge, this is the first reported case of natural transmission of an r(Y). METHODS AND RESULTS: Amplification of X chromosome polymorphisms by PCR showed that the KS was of paternal origin. G-banding and...

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