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Article

Alpha-tocopherol Modulates Hydrogen Peroxide-Induced DNA Damage and Telomere Shortening of Human Skin Fibroblasts Derived from Differently Aged Individuals

28 Jan 2010

Abstract excerpt

Antioxidants such as vitamin E may act differently on skin cells depending on the age of the skin and the level of oxidative damage induced. The effects of alpha-tocopherol (ATF) on H(2)O(2)-induced DNA damage and telomere shortening of normal human skin fibroblast cells derived from young and old individual donors were determined. Fibroblasts were divided into five groups; untreated control, H(2)O(2)-induced...

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PMID: 20112180
DOI: 10.1055/s-0029-1240812

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