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Article

Modulation of collagen synthesis and its gene expression in human skin fibroblasts by tocotrienol-rich fraction

1 Jan 2011

Abstract excerpt

INTRODUCTION: Skin aging may occur as a result of increased free radicals in the body. Vitamin E, the major chain-breaking antioxidant, prevents propagation of oxidative stress, especially in biological membranes. In this study, the molecular mechanism of tocotrienol-rich fraction (TRF) in preventing oxidative stress-induced skin aging was evaluated by determining the rate of total collagen synthesis and its gene...

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PMID: 22291837
DOI: 10.5114/aoms.2011.25567

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