Attenuated familial adenomatous polyposis: results from an international collaborative study.

doi:10.1111/j.1463-1318.2010.02218.x

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Article

Attenuated familial adenomatous polyposis: results from an international collaborative study.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Oct 2010

Knudsen A L, Bülow S, Tomlinson I, Möslein G, Heinimann K, Christensen I J

Abstract excerpt

AIM: The study aimed to describe genetical and clinical features of attenuated familial adenomatous polyposis (AFAP) and to propose clinical criteria and guidelines for treatment and surveillance. METHOD: A questionnaire study was carried out of polyposis registries with data on patients with presumed AFAP, defined as having ≤ 100 colorectal adenomas at age ≥ 25. RESULTS: One hundred and ninety-six patients were...

Topics

Adenomatous Polyposis Coli
Adolescent
Adult
Aged
Aged, 80 and over
Child
Colectomy
DNA Mutational Analysis
Female
Genes, APC
Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Mutation

Registries

Statistics, Nonparametric

Young Adult

Source

Open in PubMed

Identifiers

PMID: 20105204
DOI: 10.1111/j.1463-1318.2010.02218.x

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