Article
Efficient transient rescue of hematopoietic mutant phenotypes in zebrafish using Tol2-mediated transgenesis.
Development, growth & differentiation - 1 Feb 2010
Takeuchi Miki, Kaneko Hiroshi, Nishikawa Keizo, Kawakami Koichi, Yamamoto Masayuki, Kobayashi Makoto
Abstract excerpt
Phenotypic rescue experiments have been commonly used in zebrafish since it is convenient to study the causality of mutant phenotypes just by injecting mRNA into embryos. However, this strategy is only effective for phenotypes at early embryonic stages due to mRNA instability. For later developme...
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