Article
Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeability.
Human immunology - 1 Apr 2010
Wolters Victorien M, Alizadeh Behrooz Z, Weijerman Michel E, Zhernakova Alexandra, van Hoogstraten Ingrid M W, Mearin M Luisa, Wapenaar Martin C, Wijmenga Cisca, Schreurs Marco W J
Abstract excerpt
Various genes may influence intestinal barrier function, including MAGI2, MYO9B, and PARD3, which are associated with celiac disease. Because direct measurement of intestinal permeability is difficult, antibodies against gliadin (AGA) and Baker's yeast (anti-Saccharomyces cerevisiae antibodies [ASCA]) can be used as an indirect test. The objective of this study was to investigate whether intestinal permeability,...
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