Article
Association between a high number of isolated lymph nodes in T1 to T4 N0M0 colorectal cancer and the microsatellite instability phenotype.
Archives of surgery (Chicago, Ill. : 1960) - 1 Jan 2010
Eveno Clarisse, Nemeth Judith, Soliman Hany, Praz Françoise, de The Hugues, Valleur Patrice, Talbot Ian C, Pocard Marc
Abstract excerpt
HYPOTHESIS: Stage I or II colorectal carcinomas with microsatellite instability (MSI) are characterized by more isolated lymph nodes in the resected specimen than their counterparts with microsatellite stability (MSS). DESIGN: Prospective study. SETTING: Academic research. PATIENTS: Using a pentaplex polymerase chain reaction assay, MSI status was determined prospectively for 135 operative patients. MAIN OUTCOME...
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