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Article

Tyrosine hydroxylase is required for cuticle sclerotization and pigmentation in Tribolium castaneum.

Insect biochemistry and molecular biology - 1 Mar 2010

Gorman Maureen J, Arakane Yasuyuki

Abstract excerpt

Newly synthesized insect cuticle is soft and pale but becomes stronger (sclerotized) and often darker (pigmented) over several hours or days. The first step in the sclerotization and pigmentation pathways is the hydroxylation of tyrosine to produce 3,4-dihydroxyphenylalanine (DOPA). Tyrosine hydroxylase (TH) is known to catalyze this reaction during pigmentation, but a role for TH in sclerotization has not been...

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Identifiers

PMID: 20080183
DOI: 10.1016/j.ibmb.2010.01.004
PMCID: PMC2854195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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