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Identification, mRNA expression and functional analysis of several yellow family genes in Tribolium castaneum.

Insect biochemistry and molecular biology - 1 Mar 2010

Arakane Yasuyuki, Dittmer Neal T, Tomoyasu Yoshinori, Kramer Karl J, Muthukrishnan Subbaratnam, Beeman Richard W, Kanost Michael R

Abstract excerpt

Querying the genome of the red flour beetle, Tribolium castaneum, with the Drosophila melanogaster Yellow-y (DmY-y) protein sequence identified 14 Yellow homologs. One of these is an ortholog of DmY-y, which is required for cuticle pigmentation (melanization), and another is an ortholog of DmY-f/f2, which functions as a dopachrome conversion enzyme (DCE). Phylogenetic analysis identified putative T. castaneum...

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PMID: 20149870
DOI: 10.1016/j.ibmb.2010.01.012

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