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Article

A five‐gene signature as a potential predictor of metastasis and survival in colorectal cancer

4 Dec 2009

Abstract excerpt

To understand the molecular mechanisms of metastasis and prognosis of colorectal cancer (CRC), we isolated single cell-derived progenies (SCPs) from SW480 cells in vitro and compared their metastatic potential in an orthotopic CRC tumour model in vivo. Two groups of SCPs with the capability of high and low metastasis, respectively, were obtained. By analysing the gene expression profiles of high (SCP51), low...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20077526
DOI: 10.1002/path.2668

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