Article
Effective prediction of outcome of combination therapy with pegylated interferon alpha 2b plus ribavirin in Japanese patients with genotype-1 chronic hepatitis C using early viral kinetics and new indices.
Journal of gastroenterology - 1 Jan 2009
Nomura Hideyuki, Miyagi Yugo, Tanimoto Hironori, Higashi Masashi, Ishibashi Hiromi
Abstract excerpt
BACKGROUND: The rates of sustained virologic response (SVR) and relapse with pegylated interferon alpha 2b (peginterferon) plus ribavirin in patients with genotype-1 chronic hepatitis C (CHC) are approximately 50 and 30%, respectively. We investigated whether SVR and transient response (TR) can be differentiated during treatment using new indices calculated from early viral kinetics and the timing of when...
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