Article
677C>T and 1298A>C polymorphisms of methylenetetrahydropholate reductase gene and biochemical parameters in Turkish population with spina bifida occulta.
Turkish neurosurgery - 1 Jan 2010
Eser Betul, Cosar Murat, Eser Olcay, Erdogan Mujgan O, Aslan Adem, Yildiz Handan, Boyaci Gazi, Buyukbas Sadik, Solak Mustafa
Abstract excerpt
AIM: This study aimed to investigate the 677C > T and 1298A > C MTHFR gene polymorphisms and their metabolic effects on the levels of folate, vitamin B12 and homocysteine in the serum of Turkish spina bifida occulta (SBO) patients and healthy individuals in disease. MATERIAL AND METHODS: A case-c...
Topics
- Adenine
- Case-Control Studies
- Cytosine
- Folic Acid
- Homocysteine
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymorphism, Single Nucleotide
- Reference Values
- Spina Bifida Occulta
- Thymine
- Turkey
- Vitamin B 12