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3D PLGA scaffolds improve differentiation and function of bone marrow mesenchymal stem cell-derived hepatocytes.

Stem cells and development - 1 Sept 2010

Li Jun, Tao Ran, Wu Wei, Cao Hongcui, Xin Jiaojiao, Li Jun, Guo Jing, Jiang Longyan, Gao Changyou, Demetriou Achilles A, Farkas Daniel L, Li Lanjuan

Abstract excerpt

UNLABELLED: Liver tissue engineering with hepatic stem cells provides a promising alternative to liver transplantation in patients with acute and chronic hepatic failure. In this study, a three-dimensional (3D) bioscaffold was introduced for differentiation of rat bone marrow mesenchymal stem cells (BMSCs) into hepatocytes. For hepatocyte differentiation, third passage BMSCs isolated from normal adult F344 rats...

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PMID: 20055663
DOI: 10.1089/scd.2009.0415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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