Article
Exosomes/microvesicles as a mechanism of cell-to-cell communication.
Kidney international - 1 Nov 2010
Camussi Giovanni, Deregibus Maria C, Bruno Stefania, Cantaluppi Vincenzo, Biancone Luigi
Abstract excerpt
Microvesicles (MVs) are circular fragments of membrane released from the endosomal compartment as exosomes or shed from the surface membranes of most cell types. An increasing body of evidence indicates that they play a pivotal role in cell-to-cell communication. Indeed, they may directly stimulate target cells by receptor-mediated interactions or may transfer from the cell of origin to various bioactive...
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