Article
High-altitude adaptation of yak based on genetic variants and activity of lactate dehydrogenase-1.
Biochemical genetics - 1 Jun 2010
Kuang Liangde, Zheng Yucai, Lin Yaqiu, Xu Yaou, Jin Suyu, Li Yuping, Dong Feng, Jiang Zhongyong
Abstract excerpt
This study investigates the molecular mechanism by which yaks (Bos grunniens) adapt to hypoxia based on lactate dehydrogenase (LDH). Three LDH1 variants of the yak were revealed in tissue extracts by electrophoresis, including LDH1-F, LDH1-M, and LDH1-S. Kinetic analysis using purified LDH1 varia...
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