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Article

Hprt mutant frequency and p53 gene status in mice chronically exposed by inhalation to benzene.

Chemico-biological interactions - 19 Mar 2010

Albertini Richard J, Judice Stephen A, Recio Leslie, Walker Vernon E

Abstract excerpt

Hprt mutant frequency and p53 gene status were assessed in wild-type and p53 heterozygous (p53+/-) mice exposed chronically by inhalation to benzene. Benzene exposures to 100 ppm for 6h on Monday-Friday, 100 ppm for 10h on Monday-Wednesday-Friday, or 200 ppm for 5h on Monday-Wednesday-Friday yielded the same total exposures (concentration x time) of 3000 ppm x h/week. Hprt mutations in splenic T-lymphocytes were...

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Share to Benzene
Share to Genes, p53
Share to Hypoxanthine Phosphoribosyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inhalation Exposure

Share to Loss of Heterozygosity

Share to Lymphoma, T-Cell

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Share to Receptors, Antigen, T-Cell

Source

Identifiers

PMID: 20035728
DOI: 10.1016/j.cbi.2009.12.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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