Article
Renal cell carcinoma in children and young adults: clinicopathological, immunohistochemical, and VHL gene analysis of 46 cases with follow-up.
International journal of surgical pathology - 1 Apr 2011
Rao Qiu, Chen Jie-yu, Wang Jian-dong, Ma Heng-hui, Zhou Hang-bo, Lu Zhen-feng, Zhou Xiao-jun
Abstract excerpt
To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) gene region and screening for VHL gene mutations were performed in all tumors. Applying the 2004...
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