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Article

Prevalence and significance of MEFV gene mutations in patients with sarcoidosis.

Scandinavian journal of rheumatology - 1 Jan 2016

Sever F, Kobak S, Goksel Ö, Goksel T, Orman M, Berdeli A

Abstract excerpt

OBJECTIVES: Sarcoidosis is a chronic granulomatous disease. Pyrin has anti-inflammatory activity in the regulation of inflammasomes and is encoded by the Mediterranean fever (MEFV) gene. MEFV gene mutations trigger the inflammatory cascade and cause familial Mediterranean fever (FMF). A relationship between various rheumatic diseases and MEFV gene mutations has been demonstrated. The aim of this study was to...

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Arthritis
Blood Sedimentation
C-Reactive Protein
Cytoskeletal Proteins
Prevalence

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Identifiers

PMID: 27053370
DOI: 10.3109/03009742.2015.1092580

Genes

MEFV
CRP

Variants

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