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Article

TARDBP mutations in Parkinson's disease.

Parkinsonism & related disorders - 1 Mar 2013

Rayaprolu Sruti, Fujioka Shinsuke, Traynor Sharleen, Soto-Ortolaza Alexandra I, Petrucelli Leonard, Dickson Dennis W, Rademakers Rosa, Boylan Kevin B, Graff-Radford Neill R, Uitti Ryan J, Wszolek Zbigniew K, Ross Owen A

Abstract excerpt

Mutations of the TARDBP gene encoding TDP-43 protein have been shown to cause amyotrophic lateral sclerosis and have been reported to present with clinical heterogeneity including parkinsonism. In addition, TDP-43 pathology has been observed across a spectrum of neurodegenerative disorders, including Alzheimer's and Parkinson's disease. Herein we report the presence of a TDP-43 mutation in a patient with a...

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Identifiers

PMID: 23231971
DOI: 10.1016/j.parkreldis.2012.11.003
PMCID: PMC3582838

Genes

TARDBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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