Article
Experimental evidence on the immunopathogenesis of primary biliary cirrhosis.
Cellular & molecular immunology - 1 Jan 2010
Selmi Carlo, Meda Francesca, Kasangian Anaid, Invernizzi Pietro, Tian Zhigang, Lian Zhexiong, Podda Mauro, Gershwin M Eric
Abstract excerpt
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease for which an autoimmune pathogenesis is supported by clinical and experimental data, including the presence of autoantibodies and autoreactive T cells. The etiology remains to be determined, yet data suggest that both a susceptible genetic background and unknown environmental factors determine disease onset. Multiple infectious and chemical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.