Article
Genome evolution and the emergence of pathogenicity in avian Escherichia coli.
Nature communications - 3 Feb 2021
Mageiros Leonardos, Méric Guillaume, Bayliss Sion C, Pensar Johan, Pascoe Ben, Mourkas Evangelos, Calland Jessica K, Yahara Koji, Murray Susan, Wilkinson Thomas S, Williams Lisa K, Hitchings Matthew D, Porter Jonathan, Kemmett Kirsty, Feil Edward J, Jolley Keith A, Williams Nicola J, Corander Jukka, Sheppard Samuel K
Abstract excerpt
Chickens are the most common birds on Earth and colibacillosis is among the most common diseases affecting them. This major threat to animal welfare and safe sustainable food production is difficult to combat because the etiological agent, avian pathogenic Escherichia coli (APEC), emerges from ubiquitous commensal gut bacteria, with no single virulence gene present in all disease-causing isolates. Here, we...
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