Article
Polymorphic microsatellite markers for genetic analysis of collagen genes in suspected collagenopathies in dogs.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine - 1 Nov 2007
Temwichitr J, Hazewinkel H A W, van Hagen M A, Leegwater P A J
Abstract excerpt
Defects in collagen proteins cause a variety of disorders in humans. It can be expected that collagen gene mutations are involved in collagenopathies in dogs. The collagen genes COL3A1, COL5A1, COL5A2, COL6A1, COL6A3, COL9A1, COL9A2, COL9A3, COL10A1 and COL11A1 were identified on the canine genome based on the homology with the human genes. Simple sequence repeats (microsatellites) were found in the chromosomal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
