Article
Investigation of SERPINE1 genetic polymorphism in Macedonian patients with occlusive artery disease and deep vein thrombosis.
Kardiologia polska - 1 Oct 2009
Spiroski Igor, Kedev Sashko, Antov Slobodan, Trajkov Dejan, Petlichkovski Aleksandar, Dzhekova-Stojkova Sloboda, Kostovska Stojanka, Spiroski Mirko
Abstract excerpt
BACKGROUND: Raised SERPINE1 plasma levels are related to a 1-bp guanine deletion/insertion (4G5G) polymorphism in the promoter of the SERPINE1 (plasminogen activator inhibitor 1 - PAI1) gene. Evidence suggested that the plasma levels of SERPINE1 modulate the risk of coronary artery disease; furthermore, that the 4G5G polymorphism affects the expression of the SERPINE1 gene. AIM: To analyse association of SERPINE1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
