Article
Pilot study: association of traditional and genetic risk factors and new-onset diabetes mellitus following kidney transplantation.
Transplantation proceedings - 1 Dec 2009
Chakkera H A, Hanson R L, Raza S M, DiStefano J K, Millis M P, Heilman R L, Mulligan D C, Reddy K S, Mazur M J, Hamawi K, Moss A A, Mekeel K L, Cerhan J R
Abstract excerpt
INTRODUCTION: New-onset diabetes mellitus, which occurs after kidney transplant and type 2 diabetes mellitus (T2DM), shares common risk factors and antecedents in impaired insulin secretion and action. Several genetic polymorphisms have been shown to be associated with T2DM. We hypothesized that transplant recipients who carry risk alleles for T2DM are "tipped over" to develop diabetes mellitus in the...
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