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Article

A case of structure determination using pseudosymmetry.

Acta crystallographica. Section D, Biological crystallography - 1 Dec 2009

Radaev Sergei, Agniswamy Johnson, Sun Peter D

Abstract excerpt

Here, a case is presented of an unusual structure determination which was facilitated by the use of pseudosymmetry. Group A streptococcus uses cysteine protease Mac-1 (also known as IdeS) to evade the host immune system. Native Mac-1 was crystallized in the orthorhombic space group P2(1)2(1)2. Surprisingly, crystals of the inactive C94A mutant of Mac-1 displayed monoclinic symmetry with space group P2(1), despite...

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Identifiers

PMID: 19966420
DOI: 10.1107/S0907444909039912
PMCID: PMC2789005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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