Article
Gene genealogies strongly distorted by weakly interfering mutations in constant environments.
Genetics - 1 Feb 2010
Seger Jon, Smith Wendy A, Perry Jarom J, Hunn Jessalynn, Kaliszewska Zofia A, Sala Luciano La, Pozzi Luciana, Rowntree Victoria J, Adler Frederick R
Abstract excerpt
Neutral nucleotide diversity does not scale with population size as expected, and this "paradox of variation" is especially severe for animal mitochondria. Adaptive selective sweeps are often proposed as a major cause, but a plausible alternative is selection against large numbers of weakly deleterious mutations subject to Hill-Robertson interference. The mitochondrial genealogies of several species of whale lice...
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