Article
Cortical thickness is influenced by regionally specific genetic factors.
Biological psychiatry - 1 Mar 2010
Rimol Lars M, Panizzon Matthew S, Fennema-Notestine Christine, Eyler Lisa T, Fischl Bruce, Franz Carol E, Hagler Donald J, Lyons Michael J, Neale Michael C, Pacheco Jennifer, Perry Michele E, Schmitt J Eric, Grant Michael D, Seidman Larry J, Thermenos Heidi W, Tsuang Ming T, Eisen Seth A, Kremen William S, Dale Anders M
Abstract excerpt
BACKGROUND: Although global brain structure is highly heritable, there is still variability in the magnitude of genetic influences on the size of specific regions. Yet, little is known about the patterning of those genetic influences, i.e., whether the same genes influence structure throughout the brain or whether there are regionally specific sets of genes. METHODS: We mapped the heritability of cortical...
Topics
- Adult
- Cerebral Cortex
- Female
- Genetic Variation
- Genotype
- Humans
- Magnetic Resonance Imaging
- Male
- Phenotype
- Twins