Article
Genetic Influences on the Development of Cerebral Cortical Thickness During Childhood and Adolescence in a Dutch Longitudinal Twin Sample: The Brainscale Study.
Cerebral cortex (New York, N.Y. : 1991) - 1 Mar 2019
Teeuw Jalmar, Brouwer Rachel M, Koenis Marinka M G, Swagerman Suzanne C, Boomsma Dorret I, Hulshoff Pol Hilleke E
Abstract excerpt
Previous studies have demonstrated that cortical thickness (CT) is under strong genetic control across the life span. However, little is known about genetic influences that cause changes in cortical thickness (ΔCT) during brain development. We obtained 482 longitudinal MRI scans at ages 9, 12, and 17 years from 215 twins and applied structural equation modeling to estimate genetic influences on (1) cortical...
Topics
- Adolescent
- Cerebral Cortex
- Child
- Denmark
- Female
- Gene-Environment Interaction
- Humans
- Latent Class Analysis
- Longitudinal Studies
- Magnetic Resonance Imaging