Article
How baculovirus polyhedra fit square pegs into round holes to robustly package viruses.
The EMBO journal - 20 Jan 2010
Ji Xiaoyun, Sutton Geoff, Evans Gwyndaf, Axford Danny, Owen Robin, Stuart David I
Abstract excerpt
Natural protein crystals (polyhedra) armour certain viruses, allowing them to survive for years under hostile conditions. We have determined the structure of polyhedra of the baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV), revealing a highly symmetrical covalently cross-braced robust lattice, the subunits of which possess a flexible adaptor enabling this supra-molecular assembly to...
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