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Article

Identification of a novel conserved HLA-A*0201-restricted epitope from the spike protein of SARS-CoV

1 Dec 2009

Abstract excerpt

BACKGROUND: The spike (S) protein is a major structural glycoprotein of coronavirus (CoV), the causal agent of severe acute respiratory syndrome (SARS). The S protein is a potent target for SARS-specific cell-mediated immune responses. However, the mechanism CoV pathogenesis in SARS and the role of special CTLs in virus clearance are still largely uncharacterized. Here, we describe a study that leads to the...

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PMID: 19958537
DOI: 10.1186/1471-2172-10-61

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