Article
Cutaneous manifestations of blastic plasmacytoid dendritic cell neoplasm-morphologic and phenotypic variability in a series of 33 patients.
The American journal of surgical pathology - 1 Jan 2010
Cota Carlo, Vale Esmeralda, Viana Isabel, Requena Luis, Ferrara Gerardo, Anemona Lucia, Metze Dieter, Fink-Puches Regina, Wiesner Thomas, Cerroni Lorenzo
Abstract excerpt
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a neoplasm derived from precursors of plasmacytoid dendritic cells. Cutaneous involvement represents often the first manifestation of the disease. We studied 45 skin biopsies from 33 patients (M:F=7.25:1; median age: 71 y; age range: 30 to 89) with BPDCN to delineate histopathologic and immunophenotypic features of this disease. Patients presented with...
Topics
- Adult
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Dendritic Cells
- Female
- Humans
- Immunohistochemistry
- Leukemia
- Male
- Middle Aged