Article
Does paclitaxel-carboplatin chemotherapy in a dose-dense regimen enhance survival of BRCA-related ovarian cancer patients?
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Dec 2009
Leunen Karin, Cadron Isabelle, Van Gorp Toon, Amant Frédéric, Berteloot Patrick, Neven Patrick, Legius Eric, Vergote Ignace
Abstract excerpt
In a group of 6 BRCA-related ovarian cancer patients presenting with clinical relapse, paclitaxel-carboplatin (TC) in a dose-dense regimen was administered to evaluate the response and tolerability compared with those of the sporadic group and of the patients using a regimen administered every 3 weeks. All patients were carboplatin sensitive at the time of first relapse: 4 patients showed intermediate sensitivity...
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