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Article

Transdiagnostic phenotypes of compulsive behavior and associations with psychological, cognitive, and neurobiological affective processing.

Translational psychiatry - 10 Jan 2022

Den Ouden Lauren, Suo Chao, Albertella Lucy, Greenwood Lisa-Marie, Lee Rico S C, Fontenelle Leonardo F, Parkes Linden, Tiego Jeggan, Chamberlain Samuel R, Richardson Karyn, Segrave Rebecca, Yücel Murat

Abstract excerpt

Compulsivity is a poorly understood transdiagnostic construct thought to underlie multiple disorders, including obsessive-compulsive disorder, addictions, and binge eating. Our current understanding of the causes of compulsive behavior remains primarily based on investigations into specific diagnostic categories or findings relying on one or two laboratory measures to explain complex phenotypic variance. This...

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PMID: 35013101
DOI: 10.1038/s41398-021-01773-1
PMCID: PMC8748429

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