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Article

Modifiers of Prat, a de novo purine synthesis gene, in Drosophila melanogaster.

Genome - 1 Nov 2009

Hackett Joanne M, Clark Denise V

Abstract excerpt

Drosophila melanogaster was used to identify genes with a potential role in genetic regulation of purine biosynthesis. In this study we examine two dominant genetic modifiers of the essential gene Prat, which encodes amidophosphoribosyltransferase (EC 2.4.2.14). We found that Mod(Prat:bw)3-1 enhances Prat expression only in female heads, whereas Mod(Prat:bw)3-5 suppresses Prat in all stages and tissues examined...

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Source

Identifiers

PMID: 19935919
DOI: 10.1139/g09-070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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