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Article

Cytotoxic Constituents of the Lichen <i>Diploicia canescens</i>

17 Nov 2009

Abstract excerpt

A new diphenyl ether (1), along with 12 known compounds, was isolated from the lichen Diploicia canescens. The structure of compound 1 was elucidated by spectroscopic data analysis, and the biosynthetic origin of this product is discussed. Secalonic acids B (7), D (8), and F (9) were isolated for the first time from D. canescens. The cytotoxic activities of 1-3, 6-8, and 10 against the B16 murine melanoma and...

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PMID: 19919064
DOI: 10.1021/np9003728

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