Article
Effect of topiramate on acid-base balance: extent, mechanism and effects.
British journal of clinical pharmacology - 1 Nov 2009
Mirza Nasir, Marson Anthony G, Pirmohamed Munir
Abstract excerpt
Topiramate is licensed for the treatment of epilepsy and for migraine prophylaxis, but is also used off-licence for a wide range of indications. With the increasing use of topiramate, reports have emerged that topiramate can cause metabolic acidosis in some patients. It does this by impairing bot...
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