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Article

Association of the M1V PRKAR1A mutation with primary pigmented nodular adrenocortical disease in two large families.

The Journal of clinical endocrinology and metabolism - 1 Jan 2010

Pereira Alberto M, Hes Frederik J, Horvath Anelia, Woortman Sanne, Greene Elizabeth, Bimpaki Eirini, Alatsatianos Anton, Boikos Sosipatros, Smit Johannes W, Romijn Johannes A, Nesterova Maria, Stratakis Constantine A

Abstract excerpt

BACKGROUND: Carney complex (CNC) is a familial multiple neoplasia syndrome frequently associated with primary pigmented nodular adrenocortical disease (PPNAD), a bilateral form of micronodular adrenal hyperplasia that leads to Cushing's syndrome (CS). Germline PRKAR1A mutations cause CNC and only...

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Identifiers

PMID: 19915019
DOI: 10.1210/jc.2009-0993
PMCID: PMC2805491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19915019-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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